Folic acid is a water-soluble vitamin, also known as vitamin B9, made up of pteridine, p-aminobenzoic acid and glutamic acid. Its chemical name is pteroylglutamic acid. Folic acid plays a key role in cell division and proliferation. It is an important coenzyme for the synthesis of thymine deoxyribonucleotide (dTMP), which is required for DNA synthesis. During the S phase of the cell cycle (DNA synthesis phase), a deficiency of folic acid can lead to an impairment of DNA synthesis and affect normal cell division. For example, during hematopoiesis, the rapid proliferation of bone marrow cells requires sufficient folic acid for DNA synthesis, and folic acid deficiency may cause megaloblastic anemia. Early pregnancy is a critical period for fetal neural tube development. Adequate folic acid can prevent fetal neural tube defects such as spina bifida and anencephaly. It is generally recommended that women of childbearing age take a folic acid supplement of 0.4 to 0.8 milligrams per day from three months before they plan to become pregnant to the first three months after they become pregnant.
As an important nutrient and pharmaceutical ingredient, folic acid is widely used in the pharmaceutical field for the treatment of deficiency anemia, neural tube malformations and other diseases, and appears as an adjunctive therapeutic agent in several drug formulations. The demand for folic acid in the pharmaceutical industry is increasing with the development of medical technology and people's concern for their health conditions. Folic acid is an important nutrient that is widely added to food and health products, such as cereals, muesli, bread and milk. As people's health awareness and demand for balanced nutrition increases, the amount of folic acid added to food and healthcare products is also on the rise, driving the demand for the folic acid market.
The future production of folic acid will not only pursue the growth in output, but more importantly, ensure the purity and stability of the product. The development of folic acid production process will be centered on green, energy efficient, intelligent control and other aspects, and continue to introduce innovative products and services to cope with the ever-changing market demand. Longxin Drying continues to improve spray dryers and produces folic acid pressure spray drying tower with advanced control system, efficient heat exchange system and environmentally friendly design concept. The new equipment combines online monitoring technology and artificial intelligence algorithms, the folic acid spray dryer becomes more intelligent, able to real-time monitoring and automatically adjust the parameters of the drying process, thus further improving product quality and production efficiency.
Folic Acid Pressure Spray Drying Tower Process Flow
The Folic Acid Pressure Spray Drying Tower is capable of efficiently converting the folic acid solution into a high quality powder product while maintaining the stability of its active ingredients. This technology not only increases production efficiency, but also improves product quality and is suitable for large-scale industrialized production, while keeping the active ingredients of the product undamaged.
(1) Raw material preparation and pretreatment
Preparation of raw materials: according to a specific formula, folic acid is dissolved in a solvent (usually water) to form a folic acid solution of a certain concentration.
Pretreatment: If required, the folic acid solution is subjected to filtration or other pretreatment steps to remove impurities and insoluble particles and ensure a uniform and stable solution.
(2) Feeding system
Conveying pump: Use precision metering pump to convey the prepared folic acid solution to the pressure nozzle at the top of the drying tower.
Flow control: By adjusting the speed of the pump or valve opening, the feed rate is precisely que controlled to ensure a continuous and stable supply of material.
(3) Pressure spraying
High-pressure pumping: the folic acid solution is sent to the nozzle by the high-pressure pump, and under the action of high pressure inside the nozzle, it is sprayed out through the tiny aperture to form tiny liquid droplets.
Atomization effect: the design of the pressure nozzle makes the liquid droplets very fine and uniformly distributed, increasing the surface area, which is conducive to rapid evaporation of water.
(4) Hot air flow introduction
Heated air: fresh air is sent into the drying tower after being warmed up to the set temperature by the heating device, and comes into contact with the fine liquid droplets sprayed from the nozzles.
Air flow mode: hot air can be used to enter the drying tower in the way of parallel flow, counter flow or mixed flow, the specific choice depends on the characteristics of the product and drying requirements.
(5) Drying process
Moisture evaporation: when the hot air meets with the folic acid droplets, the moisture on the surface of the droplets evaporates rapidly, forming dry folic acid powder particles.
Short residence time: Due to the small droplet size and fast evaporation rate, the whole drying process usually takes only a few seconds, which helps to protect the heat-sensitive folic acid components from damage.
(6) Collection of product: The dried folic acid powder enters the cyclone separator with the gas flow, and is separated from the gas under the action of centrifugal force, and the collected product is further graded by vibrating screen or other means.
(7) Exhaust gas and tail gas treatment
Exhaust gas: the exhaust gas generated in the drying process is treated (e.g. cooling, dehumidification, etc.) and finally discharged into the atmosphere.
Tail gas treatment: For the tail gas that may contain trace organic matter or other pollutants, special purification treatment is also required to ensure compliance with environmental standards.
(8) Product packaging: After quality inspection, the collected folic acid powder will be put into appropriate containers and sealed and packaged for storage and transportation.
Folic acid pressure spray drying tower performance advantages
(1) Efficient and rapid drying ability
Instant drying: the liquid or slurry material is sent into the nozzle through the high-pressure pump, and very small droplets are formed under high pressure inside the nozzle, which increases the surface area and makes the water evaporate rapidly within a few seconds.
Short residence time: due to the small size of the droplets, evaporation speed, the entire drying process usually takes only a few seconds, greatly reducing the exposure time of the material at high temperatures, especially suitable for dealing with heat-sensitive substances.
(2)High quality product characteristics
Uniform particle size distribution: Pressure spray drying tower can produce powder products with uniform particle size distribution and good fluidity, which is very important for subsequent processing (e.g. preparation of tablets, capsules, etc.).
High biological activity retention rate: precise control of the feed rate, air temperature and humidity and other parameters, can effectively remove water at the same time zui limit to retain the biological activity of the material and chemical stability, to ensure product quality.
(3)Operational flexibility and adaptability
Wide applicability: it is suitable for materials with different concentrations and viscosities, and the process conditions can be adjusted according to specific needs to obtain ideal characteristics of the finished product.
High degree of automation: modern pressure spray drying tower is usually equipped with advanced automatic control system, which can monitor in real time and automatically adjust the parameters in the drying process to ensure that the production process is stable and reliable, and can be flexibly adjusted according to the needs.
(4) Safe and reliable operation
Explosion-proof design: For possible flammable and explosive risks, the equipment has taken corresponding protective measures, such as electrostatic grounding, explosion-proof motor, etc., to ensure safe operation.
Durable materials: High-quality stainless steel and other corrosion-resistant materials are selected for manufacturing, which prolongs the service life of the equipment and reduces the maintenance frequency.
(5) Multifunctionality and Expandability
Modular design: allows users to flexibly combine different functional modules according to their own needs, which is convenient for later expansion or transformation to adapt to changes in the market and technology.
Compatible with future technology: reserving interface and technology space so that new technological innovations can be easily integrated in the future to maintain the long-term competitiveness of the equipment.
(6) Energy saving and environmental protection
High energy utilization efficiency: The optimally designed heat exchange system improves energy utilization efficiency and reduces operating costs.
Low emission: the adoption of highly efficient exhaust gas treatment device reduces the emission of dust and harmful gases, which conforms to the strict environmental protection standards and at the same time reduces the impact on the environment.
(7) Enhance economic efficiency
Reduce production cost: High-efficiency drying capacity and stable production process help to increase production, reduce cost and increase enterprise profit.
Reduce waste: Fineque control and efficient drying process reduces material loss and energy waste, further enhancing economic efficiency.
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